Description

2-Hydroxy-4-[3-(Trifluoromethyl)-3H-Diazirin-3-Yl]Benzaldehyde is a specialized aromatic aldehyde derivative featuring a photoreactive diazirine group. This compound is valued for its ability to form covalent crosslinks upon UV light activation, making it an essential tool for studying biomolecular interactions. It is primarily utilized by researchers and manufacturers in the life sciences and pharmaceutical industries for photoaffinity labeling and chemical biology applications. The product is supplied with a focus on high purity and batch-to-batch consistency to ensure reliable experimental outcomes.

Application

• Photoaffinity Labeling Probes: Acts as a key photoreactive moiety for labeling proteins, nucleic acids, and other biomolecules to study binding sites and interaction networks.
• Chemical Biology Research: Used in the synthesis of probes for target identification and validation in drug discovery pipelines.
• Proteomics Studies: Incorporated into molecules to capture transient or weak protein-ligand interactions for mass spectrometry analysis.
• Material Surface Functionalization: Serves as a photo-crosslinker for modifying surfaces with specific biomolecules in biosensor development.
• Pharmaceutical Intermediate: Employed in the research and development of novel therapeutic agents that require covalent binding mechanisms.

Basic Information

Product Name	2-Hydroxy-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzaldehyde
CAS No.	308085-25-8
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-hydroxybenzaldehyde; 2-Hydroxy-4-(3-(trifluoromethyl)diazirin-3-yl)benzaldehyde; 2-Hydroxy-4-(3-trifluoromethyl-3H-diazirin-3-yl)benzaldehyde; 4-(3-Trifluoromethyl-3H-diazirin-3-yl)salicylaldehyde; Salicylaldehyde, 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]-; Benzaldehyde, 2-hydroxy-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]-; Photoaffinity Labeling Benzaldehyde Derivative
EINECS	Contact for details

Quality Control

Our production of 2-Hydroxy-4-[3-(Trifluoromethyl)-3H-Diazirin-3-Yl]Benzaldehyde adheres to stringent quality protocols to ensure it meets the exacting standards required for research and development. Each batch is characterized using advanced analytical techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and moisture absorption. Allow the container to reach room temperature before opening to prevent condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.