Description

Methyl 5-((2-Chloro-6-Fluorobenzyl)Oxy)-2-Methylbenzofuran-3-Carboxylate is a high-purity, synthetically derived benzofuran derivative that serves as a critical advanced intermediate in modern organic synthesis. Its molecular architecture, featuring a halogenated benzyloxy side chain, makes it a valuable building block for constructing complex molecules with targeted biological or material properties. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new therapeutic agents, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, or insecticides with specific activity profiles.
• Material Science Research: Used in the development of specialty polymers or organic electronic materials due to its fused heterocyclic core.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Industrial R&D: Utilized in university and corporate laboratories for methodological development and exploratory chemistry.

Basic Information

Product Name	Methyl 5-((2-Chloro-6-Fluorobenzyl)Oxy)-2-Methylbenzofuran-3-Carboxylate
CAS No.	307552-04-1
Molecular Formula	C19H16ClFO4
Molecular Weight	362.78 g/mol
Synonyms	Methyl 5-[(2-chloro-6-fluorophenyl)methoxy]-2-methyl-1-benzofuran-3-carboxylate; 5-((2-Chloro-6-fluorobenzyl)oxy)-2-methylbenzofuran-3-carboxylic acid methyl ester; 3-Benzofurancarboxylic acid, 5-[(2-chloro-6-fluorophenyl)methoxy]-2-methyl-, methyl ester; Methyl 5-((2-chloro-6-fluorobenzyl)oxy)-2-methyl-3-benzofurancarboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-((2-Chloro-6-Fluorobenzyl)Oxy)-2-Methylbenzofuran-3-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, MS) to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.