Description

2-Bromo-1-[5-(2-Pyridinyl)-2-Thienyl]-1-Ethanone is a high-value brominated ketone building block featuring a unique heterocyclic architecture. This compound is critical for advanced organic synthesis, serving as a versatile electrophilic intermediate for constructing complex molecular frameworks. It is primarily sought after by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and kinase inhibition.
• Agrochemical Research: Used in developing novel herbicides and pesticides by acting as a core scaffold for bioactive molecule design.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive bromoacetyl group, useful for protein and biomolecule conjugation studies.
• Academic & R&D: Fundamental building block in methodological organic chemistry research for constructing complex heterocyclic systems like thienopyridines.

Basic Information

Product Name	2-Bromo-1-[5-(2-Pyridinyl)-2-Thienyl]-1-Ethanone
CAS No.	306935-06-8
Molecular Formula	C11H8BrNO2S
Molecular Weight	298.16 g/mol
Synonyms	2-Bromo-1-(5-(pyridin-2-yl)thiophen-2-yl)ethan-1-one; 2-Bromo-1-[5-(2-pyridyl)-2-thienyl]ethanone; 2-Bromo-1-(5-(2-pyridinyl)-2-thienyl)ethanone; 2-Pyridin-2-yl-5-bromoacetylthiophene; 5-(2-Pyridyl)-2-thienyl bromomethyl ketone; 2-Bromo-1-(5-(2-pyridyl)thiophen-2-yl)ethanone; Ethanone, 2-bromo-1-[5-(2-pyridinyl)-2-thienyl]-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-[5-(2-Pyridinyl)-2-Thienyl]-1-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued lighting where practical.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.