Description

4-Chloro-6-Nitro-1,8-Naphthyridine-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring chloro, nitro, and nitrile substituents, makes it a versatile precursor for constructing complex nitrogen-containing heterocycles. This compound is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel 1,8-naphthyridine derivatives with potential biological activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its reactive halogen and nitro groups.
• Material Science Precursor: Serves as a building block for creating organic semiconductors, ligands for metal-organic frameworks (MOFs), and fluorescent dyes.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for library synthesis.
• Academic & Industrial R&D: Employed in methodological organic chemistry research for novel coupling and cyclization reactions.

Basic Information

Product Name	4-Chloro-6-Nitro-1,8-Naphthyridine-3-Carbonitrile
CAS No.	305370-84-7
Molecular Formula	C9H3ClN4O2
Molecular Weight	234.60 g/mol
Synonyms	4-Chloro-6-nitro-1,8-naphthyridine-3-carbonitrile; 3-Cyano-4-chloro-6-nitro-1,8-naphthyridine; 1,8-Naphthyridine-3-carbonitrile, 4-chloro-6-nitro-; 305370-84-7; 4-Chloro-6-nitro-[1,8]naphthyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and high purity, typically meeting research-grade specifications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as purity (by HPLC), identity (by IR and NMR), and impurity profiles. We adhere to strict in-house quality management protocols to support your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.