Description

1,3-Dioxane, 5,5-Dimethyl-2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a specialized organoboron compound featuring a protected boronic ester group, making it a valuable intermediate in advanced synthetic chemistry. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating advanced organic electronic materials and emissive layers.
• Polymer & Material Science: Enables the incorporation of aromatic and functional groups into polymers for specialized coatings and high-performance plastics.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in synthetic organic chemistry.

Basic Information

Product Name	1,3-Dioxane, 5,5-Dimethyl-2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	305344-39-2
Molecular Formula	C18H27BO4
Molecular Weight	318.22 g/mol
Synonyms	4-(5,5-Dimethyl-1,3-dioxan-2-yl)phenylboronic acid pinacol ester; 2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-5,5-dimethyl-1,3-dioxane; 5,5-Dimethyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3-dioxane; 4-(Dimethyldioxanyl)phenylboronic acid pinacol ester; (4-(5,5-Dimethyl-1,3-dioxan-2-yl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1,3-Dioxane, 5,5-Dimethyl-2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee the material meets the stringent requirements for research and process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.