Description

2-Chloro-N-[3-(Difluoromethoxy)Phenyl]Acetamide is a specialized organic intermediate featuring a unique difluoromethoxy-substituted aromatic ring system. This compound matters for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where the difluoromethoxy group can significantly influence biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the difluoromethoxy moiety for enhanced efficacy and environmental profile.
• Pharmaceutical Building Block: Used in medicinal chemistry research for the development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders and inflammatory diseases.
• Fine Chemical Synthesis: Serves as a versatile electrophile in amide and aryl coupling reactions for constructing complex molecular architectures in custom synthesis projects.
• Material Science Research: Investigated as a monomer or additive for developing specialty polymers with specific fluorine-related properties, such as altered surface energy or chemical resistance.

Basic Information

Product Name	2-Chloro-N-[3-(Difluoromethoxy)Phenyl]Acetamide
CAS No.	302936-08-9
Molecular Formula	C9H8ClF2NO2
Molecular Weight	235.62 g/mol
Synonyms	2-Chloro-N-[3-(difluoromethoxy)phenyl]acetamide; N-(3-(Difluoromethoxy)phenyl)-2-chloroacetamide; 2-Chloroacetamide, N-[3-(difluoromethoxy)phenyl]-; Acetamide, 2-chloro-N-[3-(difluoromethoxy)phenyl]-; 302936-08-9; 3-(Difluoromethoxy)phenyl 2-chloroacetamide
EINECS	Contact for details

Quality Control

Our 2-Chloro-N-[3-(Difluoromethoxy)Phenyl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.