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Ethyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate CAS NO 302577-73-7
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CAS No.:302577-73-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Ethyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate is a versatile and high-purity boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize novel active ingredients and functional molecules.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
- Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with tailored properties.
- Material Science: Used in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
- Chemical Research: A valuable reagent in academic and industrial R&D for constructing complex organic molecules and exploring new synthetic pathways.
- Ligand and Catalyst Development: Serves as a starting material for synthesizing novel boron-containing ligands and catalysts.
- Fine Chemical Production: Employed in the multi-step synthesis of specialty and performance chemicals.
Basic Information
| Product Name | Ethyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate |
| CAS No. | 302577-73-7 |
| Molecular Formula | C₁₃H₂₅BO₄ |
| Molecular Weight | 256.15 g/mol |
| Synonyms | Ethyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate; 2-(3-Ethoxy-3-oxopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propionic Acid Ethyl Ester; Ethyl 3-(Pinacolatoboryl)propionate; Pinacol 3-(Ethoxycarbonyl)propylboronate; 3-(Pinacolatoboryl)propionic Acid Ethyl Ester; B-(2-Carbethoxyethyl)pinacolborane |
| EINECS | Contact for details |
Quality Control
Our Ethyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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