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Ethyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate CAS NO 302577-73-7


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CAS No.:302577-73-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate is a versatile and high-purity boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to synthesize novel active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
  • Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with tailored properties.
  • Material Science: Used in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
  • Chemical Research: A valuable reagent in academic and industrial R&D for constructing complex organic molecules and exploring new synthetic pathways.
  • Ligand and Catalyst Development: Serves as a starting material for synthesizing novel boron-containing ligands and catalysts.
  • Fine Chemical Production: Employed in the multi-step synthesis of specialty and performance chemicals.

Basic Information

Product Name Ethyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate
CAS No. 302577-73-7
Molecular Formula C₁₃H₂₅BO₄
Molecular Weight 256.15 g/mol
Synonyms Ethyl 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate; 2-(3-Ethoxy-3-oxopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)propionic Acid Ethyl Ester; Ethyl 3-(Pinacolatoboryl)propionate; Pinacol 3-(Ethoxycarbonyl)propylboronate; 3-(Pinacolatoboryl)propionic Acid Ethyl Ester; B-(2-Carbethoxyethyl)pinacolborane
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Quality Control

Our Ethyl 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl) Propionate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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