Description

3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohexan-1-One is a high-value organoboron building block, specifically a protected boronic ester derivative of cyclohexanone. This compound is critical for enabling complex carbon-carbon bond formation in advanced synthetic chemistry, offering superior stability and handling compared to its boronic acid counterpart. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling and other transition-metal catalyzed reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates via cross-coupling reactions.
• Agrochemical Research & Development: Used to construct novel heterocyclic and alicyclic structures for new pesticides and herbicides.
• Materials Science & OLED Development: Serves as a building block for creating organic semiconductors, liquid crystals, and light-emitting materials.
• Academic & Industrial R&D: Essential for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis & Contract Manufacturing: Employed in the production of bespoke fine chemicals and specialty materials.
• Polymer Chemistry: Can be used to introduce functional boron-containing groups into polymer backbones for specialty polymers.

Basic Information

Product Name	3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohexan-1-One
CAS No.	302577-72-6
Molecular Formula	C12H21BO3
Molecular Weight	224.11 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexan-1-one; 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohexanone; Cyclohexanone, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-(Pinacolatoboryl)cyclohexanone; 3-Cyclohexanoneboronic acid pinacol ester; 3-Boronocyclohexanone pinacol ester
EINECS	Contact for details

Quality Control

Our production of 3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Cyclohexan-1-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and REACH standards for global supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.