Description

(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is a high-value boronic ester derivative featuring both a pinacol boronate group and a benzylic alcohol functionality. This bifunctional structure makes it a versatile and critical building block in modern synthetic chemistry, enabling precise molecular construction. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to create novel compounds with potential herbicidal, fungicidal, or insecticidal activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organocatalysts.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its conjugated aromatic system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol
CAS No.	302348-51-2
Molecular Formula	C13H19BO3
Molecular Weight	234.10 g/mol
Synonyms	4-(Hydroxymethyl)phenylboronic acid pinacol ester; [4-(Hydroxymethyl)phenyl]boronic acid pinacol ester; 4-(Pinacolboryl)benzyl alcohol; (4-(Hydroxymethyl)phenyl)boronic acid pinacol ester; 2-[4-(Hydroxymethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanol
EINECS	Contact for details

Quality Control

Our (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Methanol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive coupling reactions. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation, especially after opening the original container. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.