Description

3-Buten-2-One, 1,1,1-Trifluoro-4-(Methylamino)- is a specialized fluorinated organic building block characterized by its reactive α,β-unsaturated ketone (enone) functionality and a methylamino substituent. This compound matters for its unique trifluoromethyl group, which imparts desirable properties such as enhanced metabolic stability and lipophilicity in advanced molecular design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in medicinal chemistry, particularly for introducing the trifluoromethyl group to modulate drug-like properties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the CF₃ group can enhance biological activity.
• Advanced Material Precursor: Serves as a building block for specialty polymers and functional materials requiring fluorinated segments for specific chemical resistance or surface properties.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reactions and methodologies involving fluorinated enones and amine derivatives.
• Ligand and Catalyst Development: Potential use in synthesizing novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	3-Buten-2-One, 1,1,1-Trifluoro-4-(Methylamino)-
CAS No.	301330-75-6
Molecular Formula	C₅H₆F₃NO
Molecular Weight	153.10 g/mol
Synonyms	1,1,1-Trifluoro-4-(methylamino)but-3-en-2-one; 4-(Methylamino)-1,1,1-trifluoro-3-buten-2-one; 4-(Methylamino)-1,1,1-trifluorobut-3-en-2-one; 1,1,1-Trifluoro-4-(methylamino)-3-buten-2-one; Methylamino-trifluorobuteneone; Trifluoromethyl aminoenone; (E/Z)-4-(Methylamino)-1,1,1-trifluorobut-3-en-2-one
EINECS	Contact for details

Quality Control

Our 3-Buten-2-One, 1,1,1-Trifluoro-4-(Methylamino)- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to minimize moisture uptake and degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.