Description

2-(4-Fluorobenzoyl)-1-Benzofuran-5-Carbaldehyde is a high-purity organic building block featuring a benzofuran core functionalized with a fluorobenzoyl group and an aldehyde. This compound matters as a versatile and critical intermediate for advanced organic synthesis, enabling the construction of complex molecules with precise structural control. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the preparation of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Research: Acts as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: The reactive aldehyde group allows for conjugation, making it useful for developing fluorescent probes or affinity tags for target identification.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.
• Custom Synthesis & Scale-up: A starting point for custom manufacturing and process optimization for clients requiring specific, high-value derivatives.

Basic Information

Item	Details
Product Name	2-(4-Fluorobenzoyl)-1-Benzofuran-5-Carbaldehyde
CAS No.	300664-74-8
Molecular Formula	C16H9FO3
Molecular Weight	268.24 g/mol
Synonyms	5-Formyl-2-(4-fluorobenzoyl)benzofuran; 1-Benzofuran-5-carboxaldehyde, 2-(4-fluorobenzoyl)-; 2-(4-Fluorobenzoyl)benzofuran-5-carbaldehyde; 300664-74-8; AKOS005258209; 2-(4-Fluorobenzoyl)-5-formylbenzofuran; 2-(p-Fluorobenzoyl)benzofuran-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorobenzoyl)-1-Benzofuran-5-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.