Description

5-(Chloromethyl)Dihydro-2(3H)-Furanone (Saltdata: Free) is a versatile and reactive heterocyclic building block, specifically a chloromethyl-substituted lactone. This compound is valued for its bifunctional reactivity, where the chloromethyl group acts as an electrophile for alkylation and the lactone ring can be opened to introduce carboxylic acid functionality. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and fine chemical industries, enabling the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and novel chemical entities. The CAS number for this compound is 39928-72-8.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used to construct heterocyclic frameworks and introduce functional groups in medicinal chemistry and agrochemical research.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for specialty polymers with tailored properties.
• Ligand and Catalyst Synthesis: Employed in the preparation of novel ligands for metal complexes and organocatalysts.
• Material Science Research: Used in the development of advanced materials, including functional coatings and resins.
• Chemical Biology Probes: Facilitates the synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	5-(Chloromethyl)Dihydro-2(3H)-Furanone (Saltdata: Free)
CAS No.	39928-72-8
Molecular Formula	C5H7ClO2
Molecular Weight	134.56 g/mol
Synonyms	5-(Chloromethyl)dihydrofuran-2(3H)-one; 5-(Chloromethyl)tetrahydro-2-furanone; 4-Chloromethyl-γ-butyrolactone; γ-Butyrolactone, 4-(chloromethyl)-; 4-(Chloromethyl)butyrolactone; 3-Hydroxytetrahydrofuran-2-one, 5-(chloromethyl)-; (3-Oxotetrahydrofuran-4-yl)methyl chloride
EINECS	Contact for details

Quality Control

Our 5-(Chloromethyl)Dihydro-2(3H)-Furanone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality systems support development and commercial supply for global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.