Description

3-Thiophenecarboxaldehyde, 4-Nitro- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique nitro-substituted thiophene scaffold enables the construction of complex molecular architectures. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene ring contributes to biological activity and selectivity.
• Material Science & Organic Electronics: Acts as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and semiconductor materials.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs), leveraging its aldehyde functionality for further derivatization.
• Dye & Pigment Manufacturing: Functions as an intermediate in the synthesis of complex dyes, pigments, and imaging agents due to its electron-accepting nitro group.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	3-Thiophenecarboxaldehyde, 4-Nitro- (9Ci)
CAS No.	39920-24-6
Molecular Formula	C5H3NO3S
Molecular Weight	157.15 g/mol
Synonyms	4-Nitro-3-thiophenecarboxaldehyde; 4-Nitrothiophene-3-carbaldehyde; 3-Formyl-4-nitrothiophene; 4-Nitro-3-thiophenecarbaldehyde; 4-Nitrothiophene-3-carboxaldehyde; 3-Thiophenecarboxaldehyde, 4-nitro-; 4-Nitro-3-thienylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxaldehyde, 4-Nitro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.