Description

5-(2-Bromo-Phenyl)-4H-[1,2,4]Triazole-3-Thiol is a high-purity, heterocyclic organic compound featuring a brominated phenyl ring fused to a triazolethiol core, making it a versatile and valuable synthetic intermediate. This compound is essential for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation fungicides, herbicides, and plant growth regulators, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialized polymers, ligands for metal-organic frameworks (MOFs), and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in academic and industrial research to develop enzyme inhibitors or molecular probes, capitalizing on the reactivity of the thiol and triazole groups.
• Coordination Chemistry: Functions as a chelating ligand for various metal ions, useful in catalysis and the preparation of coordination complexes.

Basic Information

Product Name	5-(2-Bromo-Phenyl)-4H-[1,2,4]Triazole-3-Thiol
CAS No.	39751-84-3
Molecular Formula	C8H6BrN3S
Molecular Weight	256.12 g/mol
Synonyms	3-Mercapto-5-(2-bromophenyl)-1,2,4-triazole; 5-(2-Bromophenyl)-1H-1,2,4-triazole-3-thiol; 5-(2-Bromophenyl)-4H-1,2,4-triazole-3-thiol; 1,2,4-Triazole-3-thiol, 5-(2-bromophenyl)-; 2-Bromophenyl-1,2,4-triazole-3-thiol; 5-(o-Bromophenyl)-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 5-(2-Bromo-Phenyl)-4H-[1,2,4]Triazole-3-Thiol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP environments and research requiring the highest material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.