Description

1-(2-Hydroxy-4-Iodo-Phenyl)-Ethanone is a specialized iodinated aromatic ketone, serving as a crucial building block in advanced organic synthesis. Its unique structure, featuring both a phenolic hydroxyl and an iodo substituent, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing anti-inflammatory, antimicrobial, or thyroid-related therapeutics.
• Agrochemical Synthesis: Used as a building block for creating advanced pesticides, herbicides, and plant growth regulators that require halogenated aromatic structures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Essential reagent in organic synthesis laboratories for cross-coupling reactions (e.g., Suzuki, Heck) and as a scaffold for heterocyclic compound formation.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized iodinated dyes and colorants for high-performance applications.
• Ligand & Catalyst Preparation: Can be utilized to synthesize complex ligands for metal catalysis and coordination chemistry studies.

Basic Information

Product Name	1-(2-Hydroxy-4-Iodo-Phenyl)-Ethanone
CAS No.	39730-66-0
Molecular Formula	C8H7IO2
Molecular Weight	262.05 g/mol
Synonyms	2'-Hydroxy-4'-iodoacetophenone; 4'-Iodo-2'-hydroxyacetophenone; 1-(2-Hydroxy-4-iodophenyl)ethan-1-one; 2-Acetyl-5-iodophenol; 4-Iodo-2-hydroxyacetophenone; 1-(4-Iodo-2-hydroxyphenyl)ethanone; 2-Hydroxy-4-iodoacetophenone; 4-Iodosalicylacetophenone
EINECS	Contact for details

Quality Control

Our 1-(2-Hydroxy-4-Iodo-Phenyl)-Ethanone is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards where applicable, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.