Description

Methyl 3-Cyano-2-Methylpropionate is a versatile cyanoester building block with significant utility in advanced organic synthesis. Its bifunctional nature, featuring both an ester and a nitrile group, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as the synthesis of heterocycles, amino acid derivatives, and other fine chemicals.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing cyano or carboxylic acid functionalities.
• Agrochemical Synthesis: Used as a precursor in the development of herbicides, fungicides, and insecticides, leveraging its reactive sites for molecular diversification.
• Fine Chemical Production: Serves as a starting material for the manufacture of specialty chemicals, dyes, and functional materials.
• Academic & Industrial Research: Employed in method development and exploratory chemistry for creating novel compounds and libraries.
• Polymer Chemistry: Can be utilized as a monomer or co-monomer in the synthesis of specialized polymers and resins.
• Peptidomimetics: Acts as a scaffold for the synthesis of non-natural amino acids and peptide analogs.

Basic Information

Product Name	Methyl 3-Cyano-2-Methylpropionate
CAS No.	39585-12-1
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	2-Methyl-3-cyanopropanoic acid methyl ester; Methyl 2-methyl-3-cyanopropanoate; 3-Cyano-2-methylpropionic acid methyl ester; Methyl 3-cyano-2-methylpropanoate; 2-Methyl-3-cyanopropionic acid methyl ester; Methyl (2-methyl-3-cyano)propionate; 3-Cyano-2-methyl-methyl propionate
EINECS	Contact for details

Quality Control

Our Methyl 3-Cyano-2-Methylpropionate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (20°C)	1.00 - 1.05 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.