Description

4-[Bis(Trimethylsilyl)Amino]Butanoic Acid Trimethylsilyl Ester is a specialized organosilicon compound featuring a protected amino acid functionality. This molecule is highly valued as a versatile building block and protecting group reagent in advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in peptide mimetics and prodrug development.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of γ-aminobutyric acid (GABA) derivatives and other bioactive molecules with protected amine and carboxylic acid groups.
• Peptide Chemistry: Used as a reagent for introducing silyl-protected amino acid moieties, facilitating complex peptide and peptidomimetic synthesis.
• Prodrug Development: Employed in the design and synthesis of prodrugs where controlled release of the active pharmaceutical ingredient (API) is required.
• Agrochemical Synthesis: Serves as a building block for creating novel compounds with potential herbicidal or insecticidal activity.
• Material Science Research: Utilized in the synthesis of functionalized siloxanes and silicon-containing polymers for specialized applications.
• Organic Synthesis Reagent: Acts as a dual-protecting group agent and a nucleophile in various carbon-nitrogen and carbon-carbon bond-forming reactions.

Basic Information

Product Name	4-[Bis(Trimethylsilyl)Amino]Butanoic Acid Trimethylsilyl Ester
CAS No.	39508-23-1
Molecular Formula	C13H31NO2Si3
Molecular Weight	317.66 g/mol
Synonyms	4-[Bis(trimethylsilyl)amino]butyric acid trimethylsilyl ester; 4-(Bis(trimethylsilyl)amino)butanoic acid trimethylsilyl ester; γ-(Bis(trimethylsilyl)amino)butyric acid trimethylsilyl ester; TMS-GABA(TMS)2; N,N-Bis(trimethylsilyl)-4-aminobutanoic acid trimethylsilyl ester; 4-Aminobutyric acid, N,N-bis(trimethylsilyl)-, trimethylsilyl ester; Butanoic acid, 4-[bis(trimethylsilyl)amino]-, trimethylsilyl ester
EINECS	Contact for details

Quality Control

Our production of 4-[Bis(Trimethylsilyl)Amino]Butanoic Acid Trimethylsilyl Ester adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation upon prolonged exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.