Description

Nigellone CAS NO 39461-20-6 is a bioactive phytochemical compound primarily derived from the seeds of *Nigella sativa* (black cumin). This compound is valued for its potential role as a key marker and active ingredient in research and product development. It is of significant interest to industries focused on nutraceuticals, pharmaceuticals, and advanced botanical extracts, where standardized, high-purity natural compounds are essential.

Application

• Nutraceutical & Dietary Supplement Formulation: Used as a standardized bioactive component in capsules, tablets, and liquid extracts targeting wellness and immune support.
• Pharmaceutical Research & Development: Serves as a reference standard and active pharmaceutical ingredient (API) intermediate in preclinical studies for various therapeutic applications.
• Cosmeceutical Products: Incorporated into advanced skincare formulations for its potential antioxidant and skin-conditioning properties.
• Botanical & Herbal Extract Standardization: Acts as a quantitative marker to ensure the potency, consistency, and quality of *Nigella sativa* extracts.
• Food & Beverage Fortification: Utilized in functional food and beverage products designed to deliver specific health benefits.
• Academic & Analytical Research: Employed as a high-purity analytical standard in universities and testing laboratories for method development and compound identification.

Basic Information

Product Name	Nigellone
CAS No.	39461-20-6
Molecular Formula	C18H24O2
Molecular Weight	272.38 g/mol
Synonyms	Thymoquinone dimer; 2-Isopropyl-5-methyl-1,4-benzoquinone dimer; Dithymoquinone; 3,3'-Diisopropyl-5,5'-dimethyl-2,2'-bibenzoquinone; Nigellone (from Black Seed); Black Cumin Seed Quinone Dimer; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Nigellone is produced and tested under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC profiles, confirming identity, purity, and the absence of specified impurities. Specifications are designed to meet the rigorous demands of research, nutraceutical, and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled under inert conditions when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to brownish crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 3.0%
Microbiological Analysis	Meets standard guidelines for botanical extracts

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.