Description

Propionylmaridomycin is a semi-synthetic derivative of the macrolide antibiotic maridomycin, characterized by the addition of a propionyl group. This modification is significant as it can enhance the compound's antimicrobial activity, stability, or pharmacokinetic profile, making it a valuable intermediate in pharmaceutical research and development. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors focused on developing novel antibacterial agents and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced macrolide antibiotic candidates.
• Antimicrobial Research: Used in microbiological and biochemical studies to investigate mechanisms of action against resistant bacterial strains.
• Structure-Activity Relationship (SAR) Studies: Essential for medicinal chemistry programs aiming to optimize the potency and safety profile of maridomycin derivatives.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Bioconjugation & Prodrug Development: Utilized in research exploring targeted drug delivery systems and prodrug strategies to improve therapeutic efficacy.

Basic Information

Product Name	Propionylmaridomycin
CAS No.	39386-19-1
Molecular Formula	C42H71NO15
Molecular Weight	854.0 g/mol
Synonyms	Maridomycin III propionate; Propionylmaridomycin III; 3''-O-Propionylmaridomycin; 4''-O-Propionylmaridomycin A3; Maridomycin propionate ester; Antibiotic B-5050 propionate; (Commonly referenced by its research codes related to the maridomycin complex)
EINECS	Contact for details

Quality Control

Our Propionylmaridomycin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant standards for fine chemical and pharmaceutical intermediates, ensuring reliable material for your critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.