Description

2-Fluoro-4-Chloro Biphenyl is a halogenated biphenyl derivative serving as a versatile and critical organic intermediate in advanced chemical synthesis. Its value lies in its unique molecular structure, which provides a stable aromatic core with reactive halogen sites for selective functionalization, enabling the construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a fluorinated and chlorinated biphenyl scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where its halogen atoms allow for precise molecular tuning.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Organic Synthesis & Catalysis: Acts as a starting material or ligand precursor in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other catalytic processes.
• Material Science Research: Employed in the development of novel polymers, dyes, and advanced organic materials with specific electronic or physical properties.

Basic Information

Product Name	2-Fluoro-4-Chloro Biphenyl
CAS No.	39224-18-5
Molecular Formula	C12H8ClF
Molecular Weight	206.64 g/mol
Synonyms	1-Fluoro-2-(4-chlorophenyl)benzene; 4-Chloro-2-fluorobiphenyl; (4-Chlorophenyl)(2-fluorophenyl); 2-Fluoro-4'-chlorobiphenyl; Biphenyl, 2-fluoro-4-chloro-; 2-Fluor-4-chlor-biphenyl; 4-Chloro-2-fluoro-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Chloro Biphenyl is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.