Description

4-Chlorophenyl Phenylphosphoramidochloridate is a specialized organophosphorus compound that serves as a critical intermediate in advanced chemical synthesis. Its unique structure, featuring both phosphoramidate and chloridate functionalities, makes it a valuable building block for constructing complex molecules. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active molecules, including potential enzyme inhibitors and prodrugs.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized phosphorus-containing ligands used in catalysis.
• Peptide Mimetics Research: Employed in medicinal chemistry for creating phosphate and phosphonate-based peptide analogs.
• Chemical Biology Probes: Useful for synthesizing activity-based probes that target serine hydrolases and related enzymes.
• Polymer Modification: Intermediate for introducing phosphorus-based functional groups into polymer chains to alter material properties.

Basic Information

Product Name	4-Chlorophenyl Phenylphosphoramidochloridate
CAS No.	39220-34-3
Molecular Formula	C12H10Cl2NO2P
Molecular Weight	302.09 g/mol
Synonyms	Phenyl N-(4-Chlorophenoxy)phosphoramidochloridate; Phosphoramidochloridic Acid, Phenyl-, 4-Chlorophenyl Ester; 4-Chlorophenyl Phenylphosphoramidochloridate; Phenyl (4-Chlorophenoxy)phosphoramidochloridate; 4-Chlorophenoxy(phenyl)phosphoramidochloridate; NSC 163082; Phosphoramidochloridic acid, phenyl-, 4-chlorophenyl ester; (4-Chlorophenoxy)(phenyl)phosphoramidoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Chlorophenyl Phenylphosphoramidochloridate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.