Description

1-(3-Nitro-5-(Trifluoromethyl)Phenyl)Ethanone is a high-purity, specialized aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both nitro and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a nitroaryl or trifluoromethylphenyl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioavailability and stability.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex organic dyes and pigments due to its electron-withdrawing substituents.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create biaryl structures.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic pathways.

Basic Information

Product Name	1-(3-Nitro-5-(Trifluoromethyl)Phenyl)Ethanone
CAS No.	39174-87-3
Molecular Formula	C9H6F3NO3
Molecular Weight	233.15 g/mol
Synonyms	3'-Nitro-5'-(trifluoromethyl)acetophenone; 1-[3-Nitro-5-(trifluoromethyl)phenyl]ethanone; 3-Nitro-5-(trifluoromethyl)acetophenone; 3-Nitro-α,α,α-trifluoro-m-acetophenone; m-Nitro-α,α,α-trifluoroacetophenone; 1-Acetyl-3-nitro-5-(trifluoromethyl)benzene; Ethanone, 1-[3-nitro-5-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(3-Nitro-5-(Trifluoromethyl)Phenyl)Ethanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.