Description

Benzene, 2-Chloro-1,3,4-Trifluoro- is a halogenated aromatic compound of significant interest in advanced organic synthesis. This molecule serves as a versatile and critical building block for the development of complex fluorinated target compounds. It is primarily sought after by research and development laboratories and industrial manufacturers in the pharmaceutical and agrochemical sectors, where its unique substitution pattern enables the introduction of specific functionalities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a specific trifluoromethyl or chloro-fluoro aromatic core structure.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Research: Acts as a foundational unit for creating fluorinated aromatic components in electronic display and lighting materials.
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer backbones, improving chemical resistance and thermal stability.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to construct complex, multi-substituted benzene derivatives.
• Fluorine Chemistry Research: Serves as a standard or starting material in academic and industrial research focused on new fluorination methodologies and reaction mechanisms.

Basic Information

Product Name	Benzene, 2-Chloro-1,3,4-Trifluoro-
CAS No.	39153-73-6
Molecular Formula	C6H2ClF3
Molecular Weight	166.53 g/mol
Synonyms	1-Chloro-2,4,5-trifluorobenzene; 2,4,5-Trifluorochlorobenzene; 2-Chloro-1,3,4-trifluorobenzene; 2,4,5-Trifluoro-1-chlorobenzene; 2-Chloro-3,4,6-trifluorobenzene; 2,4,5-Trifluorophenyl chloride; 1-Chloro-2,4,5-trifluorobenzol
EINECS	Contact for details

Quality Control

Our Benzene, 2-Chloro-1,3,4-Trifluoro- is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for manufacturing and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.