Description

1-(2-Amino-4-Chlorophenyl)Ethanone is a key aromatic ketone building block characterized by its amino and chloro functional groups, making it a versatile intermediate for complex organic synthesis. Its primary value lies in enabling the construction of heterocyclic and pharmaceutical scaffolds, where precise molecular architecture is critical. This compound is essential for R&D chemists and production units in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, particularly those with heterocyclic structures like quinazolines, benzimidazoles, and other nitrogen-containing bioactive molecules.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging its reactive sites for further functionalization.
• Dye and Pigment Manufacturing: Used in the production of complex azo dyes and organic pigments, where the chlorophenyl moiety contributes to color fastness and molecular stability.
• Material Science Research: Employed in the development of organic semiconductors, photoactive materials, and liquid crystals due to its conjugated aromatic system.
• Chemical Research & Development: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and amination processes.

Basic Information

Product Name	1-(2-Amino-4-Chlorophenyl)Ethanone
CAS No.	39061-72-8
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	2'-Amino-4'-chloroacetophenone; 1-(2-Amino-4-chlorophenyl)ethan-1-one; 2-Acetylamino-5-chlorobenzene; 4'-Chloro-2'-aminoacetophenone; 2-Amino-4-chloroacetophenone; 4-Chloro-2-aminoacetophenone; NSC 406913; Ethanone, 1-(2-amino-4-chlorophenyl)-
EINECS	Contact for details

Quality Control

Our 1-(2-Amino-4-Chlorophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.