Description

5-Acetyl-2-Hydroxy-Benzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both acetyl and phenolic hydroxyl groups, makes it a valuable precursor for the development of complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key starting material in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where its benzonitrile core is integral to the final product's activity.
• Dye and Pigment Manufacturing: Acts as a precursor for the development of specialized dyes and colorants due to its reactive functional groups.
• Ligand and Catalyst Development: Employed in academic and industrial research for creating novel ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Fine Chemical Production: Serves as a versatile synthon for the manufacture of other high-value specialty chemicals and flavor/fragrance compounds.

Basic Information

Product Name	5-Acetyl-2-Hydroxy-Benzonitrile
CAS No.	39055-82-8
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	2-Hydroxy-5-acetylbenzonitrile; 5-Acetylsalicylonitrile; 2-Cyano-4-acetylphenol; 4-Acetyl-2-cyanophenol; 5-Acetyl-2-cyanophenol; 2-Hydroxy-5-acetylphenyl cyanide; 5-Acetyl-2-hydroxybenzonitrile; 5-Acetyl-2-hydroxy-phenyl cyanide
EINECS	Contact for details

Quality Control

Our 5-Acetyl-2-Hydroxy-Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	145 - 150 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.