Description

1(2H)-Naphthalenone, 3,4-Dihydro-2-Hydroxy-2-(1-Hydroxy-1-Phenylethyl)- is a specialized dihydronaphthalenone derivative featuring a unique hydroxy-substituted phenylethyl side chain. This compound is valued as a versatile chiral building block and synthetic intermediate in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce specific chirality and functional groups into target molecules.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including advanced materials and performance additives.
• Academic & Industrial Research: Used in methodological development and exploratory chemistry for novel reaction pathways and compound libraries.
• Agrochemical Intermediate: Potential application in the synthesis of novel, complex agrochemicals requiring specific stereochemistry.
• Ligand and Catalyst Development: The structure can be modified to create novel chiral ligands or organocatalysts for catalytic processes.

Basic Information

Product Name	1(2H)-Naphthalenone, 3,4-Dihydro-2-Hydroxy-2-(1-Hydroxy-1-Phenylethyl)-
CAS No.	38990-69-1
Molecular Formula	C18H18O3
Molecular Weight	282.33 g/mol
Synonyms	2-Hydroxy-2-(1-hydroxy-1-phenylethyl)-3,4-dihydro-1(2H)-naphthalenone; 2-(1-Hydroxy-1-phenylethyl)-2-hydroxy-3,4-dihydro-1(2H)-naphthalenone; 3,4-Dihydro-2-hydroxy-2-(1-hydroxy-1-phenylethyl)-1(2H)-naphthalenone; 1(2H)-Naphthalenone, 3,4-dihydro-2-hydroxy-2-(1-hydroxy-1-phenylethyl)-; α,α'-Dihydroxy-α-phenyl-α-(3,4-dihydro-1-oxo-2-naphthyl)ethane
EINECS	Contact for details

Quality Control

Our 1(2H)-Naphthalenone, 3,4-Dihydro-2-Hydroxy-2-(1-Hydroxy-1-Phenylethyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.