Description

(3As)-3,3Aα,4,4A,7Aα,8,9,9Aβ-Octahydro-4β-Hydroxy-4Aβ,8α-Dimethyl-3-Methylene-9β-Acetoxyazuleno[6,5-B]Furan-2,5-Dione is a complex sesquiterpene lactone derivative with a fused azulene-furan-dione structure, offering a unique chemical scaffold for advanced synthesis. This compound matters as a high-value intermediate for pharmaceutical research and fine chemical manufacturing, where its intricate molecular architecture is leveraged to build novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its complex, polycyclic framework.
• Natural Product Synthesis: Acts as an advanced intermediate in the total or semi-synthesis of complex natural products bearing sesquiterpene lactone motifs.
• Agrochemical Development: Investigated as a precursor for novel plant protection agents and bioactive agrochemicals.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high-purity, structurally sophisticated intermediates.
• Academic & Institutional Research: Utilized in universities and research institutes for studies in organic synthesis methodology and chemical biology.

Basic Information

Product Name	(3As)-3,3Aα,4,4A,7Aα,8,9,9Aβ-Octahydro-4β-Hydroxy-4Aβ,8α-Dimethyl-3-Methylene-9β-Acetoxyazuleno[6,5-B]Furan-2,5-Dione
CAS No.	38927-55-8
Molecular Formula	C19H24O6
Molecular Weight	348.39 g/mol
Synonyms	9β-Acetoxy-4β-hydroxy-4aβ,8α-dimethyldecahydro-3-methyleneazuleno[6,5-b]furan-2,5-dione; 4β-Hydroxy-4aβ,8α-dimethyl-3-methylenedecahydro-9β-(acetyloxy)azuleno[6,5-b]furan-2,5-dione; Azuleno[6,5-b]furan-2,5-dione derivative; Sesquiterpene lactone acetate; Advanced sesquiterpenoid intermediate
EINECS	Contact for details

Quality Control

Our (3As)-3,3Aα,4,4A,7Aα,8,9,9Aβ-Octahydro-4β-Hydroxy-4Aβ,8α-Dimethyl-3-Methylene-9β-Acetoxyazuleno[6,5-B]Furan-2,5-Dione is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and prolonged exposure to elevated temperatures; therefore, it is recommended to store it under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.