Description

Bis(2,2,2-Trichloroethyl) Azodicarboxylate is a specialized organic azodicarboxylate derivative, a versatile reagent widely used in synthetic organic chemistry. Its primary value lies in its role as a safe and efficient precursor for generating di-tert-butyl azodicarboxylate (DBAD) *in situ*, facilitating crucial transformations like the Mitsunobu reaction. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, reliable reagents for constructing complex molecular architectures.

Application

• Mitsunobu Reaction Reagent: Serves as a key precursor for generating the active coupling agent, enabling esterification, etherification, and other nucleophilic substitution reactions under mild conditions.
• Pharmaceutical Intermediate Synthesis: Used in the preparation of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly for introducing nitrogen-containing functional groups.
• Peptide Chemistry: Facilitates amide bond formation and other coupling steps in the synthesis of peptides and peptidomimetics.
• Agrochemical Manufacturing: Applied in the synthesis of herbicides, fungicides, and insecticides that require specific azo or hydrazine linkages.
• Polymer Modification: Utilized as a cross-linking agent or initiator in the production of specialty polymers and functional materials.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Bis(2,2,2-Trichloroethyl) Azodicarboxylate
CAS No.	38857-88-4
Molecular Formula	C6H4Cl6N2O4
Molecular Weight	387.83 g/mol
Synonyms	Azodicarboxylic Acid Bis(2,2,2-trichloroethyl) Ester; Di(2,2,2-trichloroethyl) Azodicarboxylate; BTCAD; Azodicarboxylic Acid Di(trichloroethyl) Ester; 2,2,2-Trichloroethyl Azodicarboxylate; Bis(β,β,β-trichloroethyl) Azodicarboxylate; (2,2,2-Trichloroethoxy)carbonyl Azide Dimer Precursor
EINECS	Contact for details

Quality Control

Our Bis(2,2,2-Trichloroethyl) Azodicarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards where required, ensuring a reliable supply for critical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.