Description

Dihydrograyanotoxin Ii is a diterpenoid compound belonging to the grayanotoxin family, known for its specific biological activity. This high-purity chemical is critical for research and development in pharmacology and toxicology, where precise molecular structure is paramount. It is primarily utilized by pharmaceutical researchers, toxicologists, and analytical laboratories investigating sodium channel modulation and natural product chemistry.

Application

• Pharmacological Research: As a reference standard in studies of voltage-gated sodium channel activity and neurotoxicity mechanisms.
• Toxicology Studies: For the analysis and characterization of grayanotoxin-related poisoning from natural sources like certain plants (e.g., Rhododendron species).
• Analytical Chemistry: Used as a high-purity calibration standard in chromatographic (HPLC, LC-MS) and spectroscopic methods for qualitative and quantitative analysis.
• Natural Product Isolation & Synthesis: Serves as a key intermediate or target molecule in the synthesis and structural elucidation of complex diterpenoids.
• Biochemical Assay Development: Employed in developing and validating in-vitro assays to screen for sodium channel modulators or antagonists.
• Academic & Institutional Research: Fundamental research tool in university and government labs for exploring plant-derived bioactive compounds.

Basic Information

Product Name	Dihydrograyanotoxin Ii
CAS No.	38776-76-0
Molecular Formula	C22H36O7
Molecular Weight	412.52 g/mol
Synonyms	Grayanotoxin XVIII; 3,5,6,14,16-Pentahydroxygrayan-10(20)-ene; Dihydrograyanotoxin II; 6-Deoxygrayanotoxin II; (1R,5S,6R,7R,9R,10S,14R)-14-Ethenyl-3,5,6,7,14,15-hexahydro-1,5:7,9-diepoxy-6,10-methano-2-benzoxacyclotetradecin-4,8,11,13(1H,12H)-tetraone
EINECS	Contact for details

Quality Control

Our Dihydrograyanotoxin Ii is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for reference materials, ensuring reliable and reproducible results for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under inert atmosphere at -20°C. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.