Description

[R,(-)]-4,4A,5,6,7,8-Hexahydronaphthalene-2(3H)-One is a high-purity, chiral organic compound belonging to the class of hexahydronaphthalenones. This specialized intermediate is valued for its defined stereochemistry, which is critical for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs) and other fine chemicals. It serves as a key building block for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular configuration directly impacts biological activity and material properties.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of complex drug molecules, particularly in the development of steroids, hormone modulators, and other therapeutic agents requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the enantiomeric purity of the active ingredient is essential for efficacy and environmental safety.
• Fine Chemical Production: Serves as a versatile starting material or intermediate in custom synthesis and the manufacture of specialty chemicals for various high-value industrial applications.
• Asymmetric Catalysis Research: Employed as a standard or substrate in academic and industrial R&D for developing and testing new chiral catalysts and asymmetric synthesis methodologies.
• Fragrance and Flavor Chemistry: Potential use as a precursor in the synthesis of specific, high-value odorants and flavor compounds where the stereoisomer defines the sensory profile.

Basic Information

Item	Details
Product Name	[R,(-)]-4,4A,5,6,7,8-Hexahydronaphthalene-2(3H)-One
CAS No.	38772-78-0
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(-)-4,4a,5,6,7,8-Hexahydro-2(3H)-naphthalenone; (R)-(-)-4,4a,5,6,7,8-Hexahydro-2(3H)-naphthalenone; (R)-(-)-Octalone; (R)-(-)-α,β-Octalone; (R)-4,4a,5,6,7,8-Hexahydronaphthalen-2(3H)-one; (3R)-3,4,4a,5,6,7-Hexahydro-2H-naphthalen-2-one; (R)-(-)-4,4a,5,6,7,8-Hexahydro-2-naphthalenone
EINECS	Contact for details

Quality Control

Our [R,(-)]-4,4A,5,6,7,8-Hexahydronaphthalene-2(3H)-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for use in sensitive synthetic pathways. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.