Description

Norethindrone Acetate CAS NO 38673-38-0 is a synthetic progestin steroid, widely recognized as a key active pharmaceutical ingredient (API). It is a critical component in the formulation of various hormonal therapies, valued for its potent progestational activity and stability. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for gynecological conditions, hormone replacement therapy, and contraceptive products.

Application

• Pharmaceutical API: Primary active ingredient in hormone replacement therapy (HRT) formulations for managing menopausal symptoms.
• Contraceptive Formulations: Used in combination oral contraceptives and other birth control products.
• Gynecological Treatments: Employed in therapies for endometriosis, abnormal uterine bleeding, and amenorrhea.
• Oncological Research: Investigated for potential applications in hormone-sensitive cancers.
• Veterinary Pharmaceuticals: Used in hormonal treatments for animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and research laboratories.
• Biochemical Research: Utilized in studies of progesterone receptor binding and steroid hormone action.

Basic Information

Product Name	Norethindrone Acetate
CAS No.	38673-38-0
Molecular Formula	C22H28O3
Molecular Weight	340.46 g/mol
Synonyms	Norethisterone Acetate; 19-Nor-17α-ethynyltestosterone Acetate; 17α-Ethynyl-19-nortestosterone Acetate; 17α-Ethynyl-19-norandrost-4-en-17β-ol-3-one Acetate; Norlutin Acetate; Aygestin; NET-A; NETA
EINECS	254-085-8

Quality Control

Our Norethindrone Acetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure it meets high-purity standards, including identification, assay, and impurity profile analysis. Certificates of Analysis (COA) are provided, detailing compliance with relevant specifications. We support cGMP and ICH Q7 guidelines for pharmaceutical ingredients, ensuring traceability and reliability for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.