Description

14-Hydroxyleucomycin V 3-Propanoate is a semi-synthetic derivative of the leucomycin family of macrolide antibiotics. This compound is significant for its role as a key intermediate in the synthesis of advanced pharmaceutical agents, particularly in the development of novel antibacterial drugs. It is primarily required by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in antibiotic development and chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of next-generation macrolide antibiotics.
• Antibacterial Research: Used in biochemical and microbiological research to study structure-activity relationships (SAR) of macrolides.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical labs.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for creating specialized chemical entities.

Basic Information

Product Name	14-Hydroxyleucomycin V 3-Propanoate
CAS No.	38456-05-2
Molecular Formula	C45H75NO17
Molecular Weight	902.07 g/mol
Synonyms	Leucomycin V 3-propionate; 14-Hydroxyleucomycin V 3-propanoate; 3-O-Propionyl-14-hydroxyleucomycin V; Josamycin intermediate; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione 3-propanoate
EINECS	Contact for details

Quality Control

Our 14-Hydroxyleucomycin V 3-Propanoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.