Description

(14R)-6β,14-Diacetoxygrayanotoxane-2α,3β,5,10,16-Pentol is a highly specific diterpenoid derivative belonging to the grayanotoxin family, a class of compounds known for their potent biological activity. This compound is of significant interest for advanced research and development in pharmacology and neurobiology due to its complex polyhydroxylated structure. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical and life sciences sectors, particularly those investigating ion channel modulators or developing novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified standard for analytical method development, validation, and quality control in drug discovery and manufacturing.
• Biochemical Research: Serves as a key tool compound in neuroscience research for studying voltage-gated sodium channels and their role in neuronal signaling.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a sophisticated synthetic building block in the multi-step synthesis of potential new chemical entities (NCEs) targeting neurological pathways.
• Toxicology Studies: Employed as an analytical standard in forensic and environmental toxicology to identify and quantify grayanotoxin-related compounds.
• Academic Research: Utilized in university and institutional labs for fundamental studies on natural product chemistry, structure-activity relationships (SAR), and biosynthesis.

Basic Information

Product Name	(14R)-6β,14-Diacetoxygrayanotoxane-2α,3β,5,10,16-Pentol
CAS No.	38290-01-6
Molecular Formula	C24H38O10
Molecular Weight	486.56 g/mol
Synonyms	6β,14-Diacetoxygrayanotoxane-2α,3β,5,10,16-pentol; Grayanotoxin derivative; (14R)-Grayanotoxane-2α,3β,5,10,16-pentol 6,14-diacetate; Diterpenoid pentol diacetate; 38290-01-6; Acetylgrayanotoxin; Andromedotoxin analogue
EINECS	Contact for details

Quality Control

Our (14R)-6β,14-Diacetoxygrayanotoxane-2α,3β,5,10,16-Pentol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive analytical data including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is supplied with each batch to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.