Description

Tetrakis[(Trimethylsilyl)Oxy]Succinic Acid Bis(Trimethylsilyl) Ester is a highly functionalized organosilicon compound, primarily used as a versatile silylating agent and protecting group reagent in advanced organic synthesis. Its value lies in its ability to efficiently protect multiple hydroxyl and carboxyl groups simultaneously, streamlining complex multi-step synthetic pathways. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key protecting group reagent for sensitive functional groups (e.g., diols, carboxylic acids) during the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the synthesis of advanced pesticide and herbicide intermediates where selective protection of hydroxyl groups is required.
• Specialty Polymer & Material Science: Serves as a monomer or modifying agent in the development of silicon-containing polymers, resins, and advanced materials with tailored properties.
• Analytical Chemistry: Utilized as a derivatization agent to enhance the volatility and detectability of polar compounds (like organic acids and polyols) in Gas Chromatography (GC) and GC-Mass Spectrometry (GC-MS) analysis.
• Peptide & Carbohydrate Chemistry: Acts as a protective agent for hydroxyl functionalities during the challenging synthesis of peptides, oligonucleotides, and complex carbohydrate structures.
• Cross-Coupling Reactions: Can function as a silicon-based reagent in palladium-catalyzed cross-coupling reactions (e.g., Hiyama coupling) for carbon-carbon bond formation.

Basic Information

Product Name	Tetrakis[(Trimethylsilyl)Oxy]Succinic Acid Bis(Trimethylsilyl) Ester
CAS No.	38166-10-8
Molecular Formula	C20H50O6Si6
Molecular Weight	563.1 g/mol
Synonyms	Succinic Acid, Tetrakis[(Trimethylsilyl)Oxy]-, Bis(Trimethylsilyl) Ester; Tetrakis(trimethylsiloxy)succinic Acid Bis(trimethylsilyl) Ester; Succinic Acid Tetrakis(trimethylsilyl) Ester (Derivative); 2,2,3,3-Tetrakis(trimethylsiloxy)succinic Acid Bis(trimethylsilyl) Ester; TMS-protected Succinic Acid Derivative; Hexakis(trimethylsilyl) Succinate; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Tetrakis[(Trimethylsilyl)Oxy]Succinic Acid Bis(Trimethylsilyl) Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality standards for research and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and highly volatile; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.