Description

Jolkinolide B is a bioactive diterpenoid lactone isolated from plants of the *Euphorbia* genus. This compound is of significant interest for its role as a key chemical marker and a promising scaffold in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and natural product sectors for drug discovery and analytical standard applications.

Application

• Pharmaceutical Research & Development: Serves as a reference standard and a lead compound for investigating anti-inflammatory, cytotoxic, and other pharmacological activities.
• Natural Product Chemistry: Used as a high-purity analytical standard for the identification and quantification of diterpenoids in plant extracts and herbal products.
• Biochemical Research: Employed in mechanistic studies to explore biological pathways and molecular targets due to its specific bioactivity.
• Quality Control (QC) in Herbal Medicine: Acts as a marker compound for the standardization and quality assurance of botanical raw materials and finished products containing *Euphorbia* species.
• Academic Research: Utilized in universities and research institutes for studies in phytochemistry, pharmacology, and synthetic chemistry.

Basic Information

Product Name	Jolkinolide B
CAS No.	37905-08-1
Molecular Formula	C20H26O4
Molecular Weight	330.42 g/mol
Synonyms	Jolkinolide B; (-)-Jolkinolide B; 12-Deoxy-16-hydroxyphorbol-13,16-lactone; 12-Deoxy-16-hydroxyphorbol 13,16-lactone; Euphorbia factor L2; 3,12-Dideoxy-6,7-epoxy-4,5-dihydroxy-8,11,13-phorbatrien-16,10-olide
EINECS	Contact for details

Quality Control

Our Jolkinolide B is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.