Description

Jolkinolide A CAS NO 37905-07-0 is a bioactive diterpenoid lactone isolated from plants of the *Euphorbia* genus. This compound is of significant interest for its unique chemical scaffold and potential biological activities, making it a valuable reference standard and research chemical. It is primarily sought after by researchers and developers in the pharmaceutical, biotechnology, and natural product chemistry sectors for drug discovery and phytochemical studies.

Application

• Pharmaceutical Research: Used as a high-purity reference standard in analytical method development and validation for quality control of herbal extracts and formulations.
• Drug Discovery: Serves as a key intermediate or lead compound in pharmacological studies investigating anti-inflammatory, cytotoxic, or other therapeutic properties.
• Natural Product Chemistry: Essential for the isolation, identification, and structural elucidation of compounds within the *Euphorbia* species and related botanical families.
• Academic & Institutional Research: Employed in university and institutional labs for studying diterpenoid biosynthesis, structure-activity relationships (SAR), and biological mechanisms.
• Biochemical Assays: Utilized as a precise biochemical tool in enzyme inhibition studies and cellular pathway analysis.
• Cosmeceutical Development: Investigated for potential applications in skincare formulations due to its plant-derived bioactive nature.

Basic Information

Product Name	Jolkinolide A
CAS No.	37905-07-0
Molecular Formula	C₂₀H₂₆O₅
Molecular Weight	346.42 g/mol
Synonyms	Jolkinolide A; (-)-Jolkinolide A; (4bS,5S,6aS,7R,9aS,9bS)-5,7-Dihydroxy-4b,7,9a-trimethyl-2,3,4,4b,5,6,6a,7,9,9a,9b,10-dodecahydro-1H-naphtho[2,1-c]pyran-1-one; Euphorbia Factor L1; 13-Hydroxyjolkinolide B
EINECS	Contact for details

Quality Control

Our Jolkinolide A is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. The product is light-sensitive (store away from light). For long-term storage, consider keeping the material under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.