Description

(2β,3β,14R)-2,3-Epoxygrayanotoxane-5,6β,10,14,16-Pentol 14-Acetate is a highly specialized diterpenoid derivative, a key structural analog within the grayanotoxin family. This compound is of significant interest for advanced research and development due to its complex polyhydroxylated and epoxidized structure, which serves as a critical intermediate or reference standard. It is primarily sought by pharmaceutical research organizations, agrochemical developers, and academic institutions focused on natural product chemistry, toxicology, and ion channel modulation studies.

Application

• Pharmaceutical Research & Development: Serves as a crucial reference standard and synthetic intermediate for investigating sodium channel modulators and developing novel therapeutic agents.
• Natural Product Chemistry Studies: Used as a high-purity analytical standard for the isolation, characterization, and structural elucidation of grayanotoxin analogs in plant extracts.
• Toxicology & Safety Assessment: Employed as a certified material for calibrating analytical instruments and validating methods in toxicological studies related to plant-derived toxins.
• Academic & Institutional Research: Provides a well-defined chemical entity for fundamental research in organic synthesis, medicinal chemistry, and biochemical pathway analysis.
• Agrochemical Discovery: Investigated as a lead compound or template for developing new bioactive molecules with potential insecticidal or pesticidal properties.
• Biochemical Reagent Manufacturing: Supplied to manufacturers of specialized biochemical kits and reagents for ion channel research and cell signaling studies.

Basic Information

Product Name	(2β,3β,14R)-2,3-Epoxygrayanotoxane-5,6β,10,14,16-Pentol 14-Acetate
CAS No.	37720-86-8
Molecular Formula	C22H34O8
Molecular Weight	426.5 g/mol
Synonyms	Grayanotoxin XVIII 14-acetate; 14-Acetoxygrayanotoxin XVIII; 2,3-Epoxygrayanotoxane-5,6,10,14,16-pentol 14-acetate; (2β,3β,14R)-2,3-Epoxy-5,6,10,14,16-pentahydroxygrayanotoxan-14-yl acetate; Grayanotoxin XVIII acetate; 37720-86-8; Grayanotoxin derivative
EINECS	Contact for details

Quality Control

Every batch of (2β,3β,14R)-2,3-Epoxygrayanotoxane-5,6β,10,14,16-Pentol 14-Acetate is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency, meeting the exacting standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.