Description

2-Propenal, 2-Methyl-3-(4-Nitrophenyl)- is a specialized organic compound featuring a propenal (acrolein) backbone substituted with a methyl group and a 4-nitrophenyl moiety. This unique structure makes it a valuable synthetic intermediate for constructing complex molecules, particularly in the fields of advanced materials and fine chemical synthesis. It is primarily sought by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a nitroaromatic or α,β-unsaturated carbonyl scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators where its reactive aldehyde group enables further chemical modifications.
• Organic Synthesis & Research: Acts as a versatile electrophile in Michael addition reactions and other C-C bond-forming transformations for academic and industrial R&D laboratories.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, dyes, and photoactive materials due to the conjugated system and nitro functional group.
• Chemical Biology Probe Development: Utilized in designing molecular probes and inhibitors that target specific biological pathways, leveraging its reactive aldehyde for bioconjugation.

Basic Information

Product Name	2-Propenal, 2-Methyl-3-(4-Nitrophenyl)-
CAS No.	37524-18-8
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	2-Methyl-3-(4-nitrophenyl)propenal; 3-(4-Nitrophenyl)-2-methyl-2-propenal; 4-Nitro-β-methylcinnamaldehyde; (E)-3-(4-Nitrophenyl)-2-methylacrylaldehyde; 2-Methyl-3-(p-nitrophenyl)acrolein; p-Nitro-β-methylcinnamaldehyde; (2E)-3-(4-Nitrophenyl)-2-methylprop-2-enal
EINECS	Contact for details

Quality Control

Every batch of 2-Propenal, 2-Methyl-3-(4-Nitrophenyl)- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets your specific research or process requirements. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support cGMP and ISO-guided applications where documentation and traceability are critical.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be amber-colored or kept in secondary opaque packaging. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.