Description

Methyl 2-Tetrahydrofuroate is a versatile ester derivative of tetrahydrofuran-2-carboxylic acid, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its unique structure makes it particularly significant for constructing complex molecules with specific stereochemistry, which is critical in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Fine Chemical Production: Serves as a building block for flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent in methodological development and process chemistry for constructing oxygen-containing heterocycles.
• Polymer Chemistry: Potential monomer or modifier for creating novel polymers with tailored properties.

Basic Information

Product Name	Methyl 2-Tetrahydrofuroate
CAS No.	37443-42-8
Molecular Formula	C6H10O3
Molecular Weight	130.14 g/mol
Synonyms	Methyl tetrahydro-2-furoate; Methyl tetrahydrofuran-2-carboxylate; 2-Tetrahydrofuroic acid methyl ester; Methyl 2-tetrahydrofurancarboxylate; Tetrahydro-2-furancarboxylic acid methyl ester; Methyl (tetrahydro-2-furyl)formate; Methyl α-tetrahydrofuroate
EINECS	Contact for details

Quality Control

Our Methyl 2-Tetrahydrofuroate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and chiral integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is moisture-sensitive; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.