Description

Orellanine is a potent mycotoxin and nephrotoxin primarily known for its presence in certain poisonous mushrooms of the *Cortinarius* genus. This compound is of significant interest in toxicology and biomedical research due to its specific mechanism of action on renal cells. It serves as a critical reference standard and research chemical for scientists and laboratories focused on studying nephrotoxicity, developing diagnostic methods for mushroom poisoning, and investigating potential therapeutic antidotes.

Application

• Toxicological Research: As a primary reference standard for studying the mechanisms of nephrotoxicity and acute kidney injury.
• Biomedical Analysis: Used in the development and validation of analytical methods (e.g., HPLC, LC-MS) for detecting orellanine in biological samples.
• Forensic Science: Employed as a calibrant in forensic investigations related to mushroom poisoning incidents.
• Pharmaceutical Development: Serves as a tool compound in preclinical research aimed at discovering treatments or antidotes for orellanine poisoning.
• Academic Studies: Utilized in university and institutional research to understand the biochemistry and pathology of mycotoxins.
• Diagnostic Kit Manufacturing: Acts as a key component in producing quality control materials for diagnostic assays targeting mushroom toxins.

Basic Information

Product Name	Orellanine
CAS No.	37338-80-0
Molecular Formula	C10H8N2O6
Molecular Weight	252.18 g/mol
Synonyms	Orellanin; 3,3',4,4'-Tetrahydroxy-2,2'-bipyridine-1,1'-dioxide; 2,2'-Bipyridine-3,3',4,4'-tetrol 1,1'-dioxide; Cortinarius toxin
EINECS	Contact for details

Quality Control

Our Orellanine is produced and handled under strict quality management protocols to ensure high purity and batch-to-batch consistency, essential for reliable research outcomes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for research chemicals, ensuring the material's integrity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	Yellow to brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.