Description

Penitremc CAS NO 37318-84-6 is a potent mycotoxin belonging to the tremorgenic indole diterpene class, known for its specific biological activity. This high-purity compound is critical for research and development in toxicology and pharmacology, serving as a reference standard and investigative tool. It is primarily utilized by analytical laboratories, academic research institutions, and pharmaceutical companies focused on neurotoxicology, food safety, and veterinary diagnostics.

Application

• Analytical Reference Standard: Used for the qualitative and quantitative analysis of mycotoxins in food, feed, and environmental samples via HPLC, LC-MS/MS, and ELISA methods.
• Pharmacological Research: Employed in neuroscience studies to investigate tremorgenic mechanisms, neuronal ion channel function, and the pathophysiology of mycotoxicoses.
• Toxicology Studies: Serves as a key toxin in model systems for assessing the effects of fungal contamination and developing detoxification strategies.
• Veterinary Diagnostics: Acts as a calibrant in diagnostic assays for detecting penitrem intoxication in animals, a condition often linked to spoiled food ingestion.
• Biochemical Research: Used to study the inhibition of high-conductance calcium-activated potassium (BK) channels and other specific cellular targets.
• Quality Control & Method Development: Essential for validating analytical methods, ensuring accuracy, and maintaining compliance in laboratory quality assurance programs.

Basic Information

Product Name	Penitremc
CAS No.	37318-84-6
Molecular Formula	C37H44ClNO6
Molecular Weight	634.20 g/mol
Synonyms	Penitrem A; Penitrem; Tremortin; 6,7-Seco-11,36-epoxy-8,20:14,32:23,33-triepoxy-12,15-cyclo-12,14-methano-12H-34,11-(epoxymethano)indolo[2',3':8,1]pyrido[3,4-b]indolo[1,2-a][1,4,13]oxadiazacyclooctadecine-10,13,16,18,21,23,26,28,30,35,38-undecone, 6-chloro-4,5,9,22,24,31-hexahydro-17,19-dihydroxy-3-[(1E)-3-methyl-1-buten-1-yl]-1,27-dimethoxy-, (1R,3E,5S,6R,8R,9R,12R,14R,15R,16R,17S,19S,20S,22S,23R,24R,26S,27S,28R,30R,31R,32R,33R,34S,35R,38S)-
EINECS	Contact for details

Quality Control

Every batch of Penitremc is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chromatographic purity assays and spectroscopic identification, to ensure compliance with industry standards for reference materials. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. The product is light-sensitive (store away from light). Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.