Description

2-(1-Methylpiperidin-4-Ylidene)Acetonitrile is a versatile nitrile-functionalized piperidine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a reactive cyano group adjacent to a cyclic enamine, makes it a valuable precursor for constructing complex nitrogen-containing heterocycles and pharmacophores. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its nitrogen-rich heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and dyes.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and novel heterocycle formation.

Basic Information

Product Name	2-(1-Methylpiperidin-4-Ylidene)Acetonitrile
CAS No.	37123-91-4
Molecular Formula	C8H12N2
Molecular Weight	136.20 g/mol
Synonyms	1-Methyl-4-(cyanomethylene)piperidine; 4-(Cyanomethylene)-1-methylpiperidine; 1-Methyl-4-(cyanomethylene)piperidine; 2-(1-Methyl-4-piperidinylidene)acetonitrile; (1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)acetonitrile; 4-(Cyanomethylene)-N-methylpiperidine
EINECS	Contact for details

Quality Control

Our 2-(1-Methylpiperidin-4-Ylidene)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and consistent performance in sensitive synthetic pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.