Description

2-(2,3,5,6-Tetramethylphenyl)Acetic Acid is a specialized aromatic carboxylic acid derivative characterized by its unique tetramethyl-substituted phenyl ring. This compound serves as a valuable high-purity synthetic intermediate and building block in advanced organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for sterically hindered compounds.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators requiring specific steric properties.
• Ligand and Catalyst Precursor: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Advanced Material Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where the bulky tetramethylphenyl group influences material properties.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals requiring specific aromatic substitution patterns.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including C-H activation and cross-coupling reactions.

Basic Information

Product Name	2-(2,3,5,6-Tetramethylphenyl)Acetic Acid
CAS No.	37051-68-6
Molecular Formula	C12H16O2
Molecular Weight	192.26 g/mol
Synonyms	(2,3,5,6-Tetramethylphenyl)acetic acid; 2,3,5,6-Tetramethylbenzeneacetic acid; α-(2,3,5,6-Tetramethylphenyl)acetic acid; Durenylacetic acid; 2-(Durenyl)acetic acid; TMPhAA; 37051-68-6; Acetic acid, 2-(2,3,5,6-tetramethylphenyl)-
EINECS	Contact for details

Quality Control

Our production of 2-(2,3,5,6-Tetramethylphenyl)Acetic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.