Description

2-Fluoro-10-Hydroxy-8-Methyl-10H-Phenoxaphosphine 10-Oxide is a specialized organophosphorus compound with a unique phenoxaphosphine oxide core structure, serving as a high-value intermediate in advanced chemical synthesis. Its molecular architecture, featuring both a fluorine substituent and a hydroxy group, makes it a critical precursor for developing novel materials and active pharmaceutical ingredients (APIs). This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate complex phosphine-based functionalities.

Application

• As a key pharmaceutical intermediate in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Utilized as a ligand precursor in transition metal catalysis for asymmetric synthesis and cross-coupling reactions.
• Acts as a building block for advanced materials, including flame retardants and specialty polymers with enhanced thermal stability.
• Employed in agrochemical research for the development of new-generation herbicides and plant growth regulators.
• Serves as a research chemical in academic and industrial laboratories studying organophosphorus chemistry and reaction mechanisms.
• Potential use in the development of OLED materials and other electronic chemicals due to its conjugated system.

Basic Information

Product Name	2-Fluoro-10-Hydroxy-8-Methyl-10H-Phenoxaphosphine 10-Oxide
CAS No.	37041-12-6
Molecular Formula	C₁₃H₁₀FO₂P
Molecular Weight	248.19 g/mol
Synonyms	10H-Phenoxaphosphine 10-oxide, 2-fluoro-10-hydroxy-8-methyl-; 2-Fluoro-8-methyl-10H-phenoxaphosphinine 10-ol 10-oxide; 8-Methyl-2-fluoro-10-hydroxy-10H-phenoxaphosphine 10-oxide; Phenoxaphosphine oxide, 2-fluoro-10-hydroxy-8-methyl-; 37041-12-6; 2-Fluoro-10-hydroxy-8-methylphenoxaphosphine 10-oxide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-10-Hydroxy-8-Methyl-10H-Phenoxaphosphine 10-Oxide is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.