Description

1-Phenyl-2-(4-Pyrimidinyl)-Ethanone is a high-purity organic building block featuring a phenyl and a pyrimidinyl moiety linked by an ethanone bridge. This compound is valued for its role as a versatile synthetic intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the pyrimidine ring's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials and photoactive compounds due to its conjugated structure.
• Academic & Contract Research: Essential for methodological studies in organic synthesis and medicinal chemistry within university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	1-Phenyl-2-(4-Pyrimidinyl)-Ethanone
CAS No.	36912-83-1
Molecular Formula	C₁₂H₁₀N₂O
Molecular Weight	198.22 g/mol
Synonyms	4-Pyrimidinyl Phenyl Ketone; 2-Pyrimidin-4-yl-1-phenylethanone; 1-Phenacylpyrimidine; 4-Acetylpyrimidine, Phenyl Derivative; 4-Benzoylpyrimidine; (4-Pyrimidinyl)(phenyl)methanone; 36912-83-1; Ethanone, 1-phenyl-2-(4-pyrimidinyl)-
EINECS	Contact for details

Quality Control

Every batch of 1-Phenyl-2-(4-Pyrimidinyl)-Ethanone is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.