Description

3-Methyl-3H-Diazirine-3-Ethanamine is a specialized heterocyclic organic compound featuring a highly reactive diazirine ring. This compound matters as a versatile photoaffinity labeling agent and crosslinking reagent, enabling the study of biomolecular interactions and protein structures. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for applications in chemical biology and proteomics.

Application

• Photoaffinity Labeling: Used to covalently tag and identify biological targets, such as proteins and nucleic acids, upon UV light activation.
• Bioconjugation & Crosslinking: Serves as a key reagent for creating stable crosslinks between biomolecules to study interaction sites and complex formation.
• Proteomics Research: Employed in mapping protein-protein interactions and identifying binding sites of small molecule drugs.
• Chemical Probe Development: Integral to synthesizing activity-based probes for functional studies in living cells.
• Material Science: Applied in surface modification and the creation of functionalized polymers with specific reactive groups.
• Diagnostic Reagent Synthesis: Used in the development of reagents for diagnostic assays and imaging.

Basic Information

Product Name	3-Methyl-3H-Diazirine-3-Ethanamine
CAS No.	36902-22-4
Molecular Formula	C5H9N3
Molecular Weight	111.15 g/mol
Synonyms	3-(2-Aminoethyl)-3-methyldiazirine; 3-Methyl-3-(2-aminoethyl)diazirine; 2-(3-Methyl-3H-diazirin-3-yl)ethan-1-amine; 3-Methyl-3H-diazirine-3-ethanamine; Diazirine-3-ethanamine, 3-methyl-; Photoaffinity Labeling Reagent; Crosslinker Reagent; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 3-Methyl-3H-Diazirine-3-Ethanamine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and meet the stringent requirements of the life sciences industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and reactivity. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.