Description

1-O,2-Seco-1,15,16-Trideoxypodolactone B is a specialized diterpenoid lactone derivative, a compound of significant interest in advanced organic synthesis and pharmaceutical research. Its unique seco-podolactone structure makes it a valuable intermediate for developing novel bioactive molecules and exploring complex natural product analogs. This high-purity compound is primarily sought by research institutions and pharmaceutical development companies engaged in medicinal chemistry, process development, and the synthesis of potential therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of complex natural product analogs and new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies to develop compounds with potential biological activity.
• Process Chemistry & Scale-Up: Employed in route development and optimization for the production of target molecules at laboratory and pilot scales.
• Academic Research: Utilized in universities and research institutes for studies in organic synthesis methodology, total synthesis, and chemical biology.
• Reference Standard: Acts as a high-purity analytical standard for quality control and identification in related chemical processes.

Basic Information

Product Name	1-O,2-Seco-1,15,16-Trideoxypodolactone B
CAS No.	36895-12-2
Molecular Formula	C20H28O5
Molecular Weight	348.43 g/mol
Synonyms	1-O,2-Seco-1,15,16-trideoxypodolactone B; Podolactone B derivative; Secopodolactone; (1R,2S,4aS,8aS)-1,2,4a,5,6,7,8,8a-Octahydro-1,4a-dimethyl-7-methylene-2-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]-1-naphthalenecarboxylic acid methyl ester; 2-O-Angeloyl-1-O-deacetyl-1,15,16-trideoxypodolactone B
EINECS	Contact for details

Quality Control

Our 1-O,2-Seco-1,15,16-Trideoxypodolactone B is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.