Description

1-(4-Fluoro-Phenyl)-2-Pyrimidin-4-Yl-Ethanone is a high-purity fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, leveraging the fluorophenyl and pyrimidine motifs for enhanced bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of specialized organic ligands and functional molecules used in electronic materials.
• Academic & Industrial R&D: Employed in method development and as a reference standard in analytical chemistry and process optimization studies.
• Fine Chemical Manufacturing: Integral to custom synthesis and contract manufacturing of high-value, complex organic molecules.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-2-Pyrimidin-4-Yl-Ethanone
CAS No.	36827-98-2
Molecular Formula	C₁₂H₉FN₂O
Molecular Weight	216.21 g/mol
Synonyms	4'-Fluoro-4-pyrimidinylacetophenone; 1-(4-Fluorophenyl)-2-(pyrimidin-4-yl)ethanone; 4-Pyrimidinyl 4-fluorophenyl ketone; 2-Pyrimidin-4-yl-1-(4-fluorophenyl)ethanone; 4-Acetylpyrimidine, 4'-fluoro derivative; Ethanone, 1-(4-fluorophenyl)-2-(4-pyrimidinyl)-; (4-Fluorophenyl)(pyrimidin-4-yl)methanone (tautomeric form)
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-Phenyl)-2-Pyrimidin-4-Yl-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.