Description

3,4,5-Trimethoxy-α-(1-Methylethyl)Phenylacetonitrile is a high-purity, versatile chemical intermediate characterized by its unique aromatic nitrile structure with methoxy and isopropyl substituents. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers engaged in developing active pharmaceutical ingredients (APIs), fine chemicals, and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, dyes, and pigments requiring specific aromatic nitrile frameworks.
• Research & Development: Essential for academic and industrial R&D in organic chemistry, medicinal chemistry, and process development.
• Liquid Crystal & Electronic Materials: Potential intermediate in the synthesis of organic electronic materials and liquid crystal compounds.

Basic Information

Product Name	3,4,5-Trimethoxy-α-(1-Methylethyl)Phenylacetonitrile
CAS No.	36622-33-0
Molecular Formula	C15H21NO3
Molecular Weight	263.33 g/mol
Synonyms	α-Isopropyl-3,4,5-trimethoxyphenylacetonitrile; 2-(3,4,5-Trimethoxyphenyl)-3-methylbutyronitrile; (3,4,5-Trimethoxyphenyl)(1-methylethyl)acetonitrile; 3,4,5-Trimethoxy-α-isopropylbenzeneacetonitrile; 36622-33-0; TMIPAN; Isopropyl-trimethoxy-phenylacetonitrile
EINECS	Contact for details

Quality Control

Our production of 3,4,5-Trimethoxy-α-(1-Methylethyl)Phenylacetonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (IR, NMR), to verify identity and assay. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We operate in compliance with cGMP principles where applicable, ensuring the material meets the exacting standards required for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be sensitive to prolonged exposure to moisture and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.