Description

Ikarugamycin is a potent, macrocyclic dilactone antibiotic originally isolated from *Streptomyces* species. This compound matters for its significant biological activity, primarily functioning as a selective inhibitor of angiogenesis and exhibiting potent antifungal properties. It is needed by researchers in pharmaceutical development, agrochemical R&D, and academic institutions focused on oncology, microbiology, and cell biology studies. Ikarugamycin CAS NO 36531-78-9 represents a high-purity biochemical tool for investigating cellular processes and developing novel therapeutic agents.

Application

• Pharmaceutical Research: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in anti-cancer and anti-angiogenesis drug discovery programs.
• Antifungal Agent Development: Serves as a lead compound for developing new agrochemicals and pharmaceuticals targeting fungal pathogens.
• Biochemical Research: Employed as a selective tool in cell biology to study angiogenesis, endothelial cell function, and related signaling pathways.
• Microbiology Studies: Used in research to investigate its mechanism of action against various Gram-positive bacteria and fungi.
• Academic & Institutional R&D: Supplied to universities and research institutes for fundamental studies in natural product chemistry and bioactivity.
• Standards & Controls: Provides a high-purity certified reference material for analytical method development and quality control in related manufacturing.

Basic Information

Product Name	Ikarugamycin
CAS No.	36531-78-9
Molecular Formula	C₂₅H₃₅NO₅
Molecular Weight	429.55 g/mol
Synonyms	Ikarugamycin; Antibiotic IC 101; Antibiotic IC-101; IC 101; IC-101; (3E,5E,8E,10E,12E,14E,19E)-13-Ethyl-4,16-dihydroxy-3,5,8,10,12,14,19-heptamethyl-22-oxa-2,9,15,18-tetraazatricyclo[18.3.1.17,11]pentacosa-1(24),3,5,7(25),8,10,12,14,19,21-decaene-6,17-dione
EINECS	Contact for details

Quality Control

Our Ikarugamycin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and structural verification via spectroscopic methods (NMR, MS), to ensure compliance with high-grade research material standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.